Symptoms of Long COVID

Symptoms of COVID-19 can last months — or even longer — after infection with SARS-CoV-2, the virus that causes COVID-19. Symptoms vary from person to person and can affect almost any part of the body.

What Is Long COVID?

Many people recover fully within a few days or weeks after being infected with SARS-CoV-2, the virus that causes COVID-19. But others have symptoms that linger for weeks, months, or even years after their initial diagnosis. Some people seem to recover from COVID-19 but then see their symptoms return, or they develop new symptoms within a few months. Even people who had no symptoms when they were infected can develop symptoms later. Either mild or severe COVID-19 can lead to long-lasting symptoms.

Long COVID, long-haul COVID, post-COVID-19 condition, chronic COVID, and post-acute sequelae of SARS-CoV-2 (PASC) are all names for the health problems that some people experience within a few months of a COVID-19 diagnosis. Symptoms of Long COVID may be the same or different than symptoms of COVID-19. Long COVID can also trigger other health conditions, such as diabetes or kidney disease.

Symptoms of Long COVID

Click on any hotspot on the human body to learn more about Long COVID symptoms.

  • Whole Body
  • Brain and Nerves
  • Eyes
  • Ears
  • Smell and Taste
  • Neck
  • Lungs
  • Heart and Blood
  • Kidneys
  • Hands
  • Legs and Feet
  • Reproductive Systems
  • Digestive Systems
  • Skin and Hair
  • Muscles and Bones
Long Covid Body


Whole Body

  • Tiredness or a lack of energy that interferes with daily life
  • Symptoms that get worse after physical or mental activity
  • Fever and chills
  • Sleep problems including insomnia, extreme daytime sleepiness, and restless leg syndrome
  • Weakness
x Whole Body


Brain and Nerves

  • Brain fog (problems with thinking, concentrating, remembering, and learning)
  • Headaches
  • Dizziness upon standing
  • Mood symptoms (feeling sad, stressed, tense, or angry) that interfere with daily life
  • Mental health conditions such as anxiety, depression, or post-traumatic stress disorder
  • Tingling, numbness, and nerve damage
  • Seizures
x Brain and Nerves



  • Changes in vision
  • Eye redness
  • Yellowish eyes (jaundice, a symptom of liver disease)
x Eyes



  • Hearing loss
x Ears


Smell and Taste

  • Stuffy nose
  • Loss of taste or distorted sense of taste
  • Loss of smell or distorted sense of smell
  • Loss of appetite
  • Increased thirst (a symptom of diabetes triggered by COVID-19)
x Smell and Taste



  • Neck pain that spreads toward the ears (from a swollen thyroid gland)
x Neck



  • Shortness of breath
  • Cough
  • Cough that may produce mucus from lungs
x Lungs


Heart and Blood

  • Chest pain
  • Rapid or irregular heartbeat
  • Fainting
x Heart and Blood



  • Pain on the side of the body (symptom of kidney problems)
  • Changes in urination
x Kidneys



  • Shaking
x Hands


Legs and Feet

  • Swelling in legs or feet
x Legs and Feet


Reproductive Systems

  • Erectile dysfunction
  • Changes in menstrual cycle
  • Short-term reduced male fertility
x Reproductive Systems


Digestive Systems

  • Stomach pain
  • Changes in appetite
  • Diarrhea
  • Constipation
  • Changes in stool color
x Digestive Systems


Skin and Hair

  • Rashes
  • Hair loss
  • Yellowish skin (jaundice, a symptom of liver damage)
x Skin and Hair


Muscles and Bones

  • Muscle aches
  • Joint pain
  • Reduced mobility
x Muscles and Bones

What We Know About Long COVID

What causes Long COVID?

Scientists don’t know for sure what causes Long COVID, but research is providing some clues.

  • SARS-CoV-2 particles may become active again, causing symptoms to reappear.

  • Overactive immune cells may release high levels of inflammatory substances that can injure organs and tissues.

  • The infection may cause the immune system to start making autoantibodies that attack a person’s own organs and tissues.

Symptoms may also be caused by a combination of these and other factors. Research into these factors is ongoing.

Why are Long COVID symptoms so varied?

Scientists are uncovering risk factors for Long COVID and reasons why symptoms vary from person to person. Some factors that may be important include:

  • Female sex

  • Older age

  • Severity of initial COVID-19 illness

  • Immune response to initial infection

  • Not being fully vaccinated against COVID-19

  • The SARS-CoV-2 variant that caused the initial infection

  • Preexisting health conditions, such as diabetes, lung problems, autoimmune diseases, or obesity

Health inequities may also increase the risk of Long COVID for some racial or ethnic minority groups and some people with disabilities.

Can children get Long COVID?

Children and teenagers can get Long COVID, whether they had COVID-19 symptoms or not.

Multisystem inflammatory syndrome in children (MIS-C) is a serious delayed complication of SARS-CoV-2 infection that may develop in children and young adults. The condition is caused by inflammation of body parts, including the heart, lungs, kidneys, brain, skin, eyes, and gastrointestinal organs. Children ages 5 to 11 are most frequently affected by MIS-C.

How can I prevent Long COVID?

The only known way to prevent Long COVID is to avoid getting COVID-19. The Centers for Disease Control and Prevention (CDC) has steps you can take to protect yourself and others from getting COVID-19.

I have COVID-19. How can I reduce my chances of getting Long COVID?

If you are not vaccinated, vaccination after you recover from COVID-19 may help to prevent Long COVID. COVID-19 vaccination may also reduce the likelihood of MIS-C in young people ages 12 to 18.

People who test positive for COVID-19 can check with their health care providers about authorized treatments that may lower their risk of severe symptoms and hospitalization. Scientists are studying COVID-19 treatments to see whether they lower the risk of long-term symptoms.

What can I do if I have Long COVID?

There is no specific treatment for Long COVID yet. You and your health care provider can work together to create a personal care plan to manage your symptoms and improve your quality of life.

There are tools available to help people cope with Long COVID and get the health and social support they need. There are also many support groups to help people with Long COVID symptoms connect with each other. The National Institute of Mental Health offers tips for managing stress during pandemics.

How You Can Help Fight Long COVID

Long COVID Clinical Studies

NIH launched the Researching COVID to Enhance Recovery (RECOVER) Initiative in early 2021 to identify risk factors and causes of Long COVID to help understand how it can be prevented or treated in the future. Your experiences — whether you have long-term COVID-19 symptoms, had COVID-19 and recovered, recently tested positive for COVID-19, or never had COVID-19 — are critical to helping scientists study these symptoms.

Reach out if you or someone you know might be interested in volunteering for a study. Compensation may be available. Pregnant people can participate, and children can also take part in some studies if they wish to and if they have the consent of a parent or guardian.

Participate in an Adult Long COVID Study

Participate in a Pediatric Long COVID Study

Long COVID Resources

If you think you or your child has Long COVID or a post-COVID condition, speak with a health care provider to set up a care plan to enhance recovery.

The Researching COVID to Enhance Recovery (RECOVER) Initiative seeks to understand, prevent, and treat long-term health effects related to COVID-19.

Coping with the long-term symptoms of COVID-19 is not easy. The CDC has some suggestions that can help.

On April 5, 2022, the White House announced that the U.S. Department of Health and Human Services would coordinate the first-ever interagency national research action plan on Long COVID.

Page last updated: October 5, 2022